I nod my head at what you're saying; it makes sense for TLG to revisit this theme. And while we are not to the point of beating a dead horse with the whole "humans vs aliens" topic because it will always appeal to children, I do think it is healthy for LEGO to change the direction and purpose of the next Space line. Classic Space is a great runner up.
I do think however that LEGO has many themes to dig up and modernize, not just Classic Space. Hence LEGO revisiting Space Police, they could just as easily revisit a polar Space theme, UFO Space theme, or organize a new theme altogether, perhaps an amalgamation of Aquazone and astronauts. We keep seeing homages to Blacktron and Classic Space, and since LEGO really hasn't abandoned the trend of fitting two species/enemies into its action themes, one could hope LEGO will make Blacktron the aggressor to a civilian CS in the very least.
Aimless dreaming aside, I look forward to see what LEGO will do with their cherished past themes we are so wanting to see return.